MEMBERS


Zhi Xie, M.D., Ph.D.
Email:zhi.xie@outlook.com
Linkedin


Dr. Xie is a professor of Bioinformatics and Genomics, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. He also holds an appointment as Director of Big Data Center for Biomedicine, Sun Yat-sen University.

Dr. Xie received two undergraduate degrees in Applied Computing and Medical Science in New Zealand and China, respectively. In 2007, he obtained his Ph.D. in Computational Systems Biology at Lincoln University, New Zealand. After three years of postdoctoral fellowship at Wilmer Institute of Johns Hopkins University, he moved to National Institutes of Health, U.S., first as a Staff Scientist and then an Investigator during 2010 to 2013. In October, 2013, he started his position at Sun Yat-sen University, leading the Laboratory of Bioinformatics and Genomics.

Research experience
2013.10 – Present     Professor in Bioinformatics and Genomics
ZhongShan Ophthalmic Center,
National Key Laboratory of Ophthalmology,, Sun Yat-sen University, Guangzhou, China

2012.09 – 2013.10    Investigator
Division of Cancer Treatment and Diagnosis, National Cancer Institute, Shady Groove, MD, USA

2010.08 – 2012.09    Staff Scientist
Center for Human Immunology, National Institutes of Health, Bethesda, MD, USA

2007.09 – 2010.08    Postdoctoral Research Fellow
Wilmer Institute, School of Medicine, Johns Hopkins University, Baltimore, MD, USA

Education
2004.02 – 2007.09    Ph.D. in Computational Systems Biology
Lincoln University, Canterbury, New Zealand

2002.02 – 2004.01    Bachelor in Applied Computing with First Class Honours
Lincoln University, Canterbury, New Zealand

1993.09 – 1998.07     Bachelor in Clinical Medicine
Chongqing University of Medical Science, Chongqing, China


Research interest

(1)    Regulation of Gene expression
(2)    Single cell sequencing and data analysis
(3)    Single molecule sequencing and data analysis
(4)    Deep learning in biomedicine
 
Scientific Service
President of Guangdong Society of Bioinformatics
Director of Big Data Center for Biomedicine, Sun yat-sen University



    谢志,教授,临床医学和计算机科学双重学位,中山眼科中心及眼科学国家重点实验室教授、中山大学生物医学大数据中心主任、中山大学学术委员会委 员,2013年回国前任美国国家癌症研究院研究员。2013年入选“千人计划”青年项目。 现任广东省生物信息学会理事长、广东省精准医学大数据工程中心执行主任。
    长期从事生物信息学研究,主要成果(1)开发第三代基因测序数据分析工具,集成三代测序序列比对,校正和组装为一体的系统,与目前的三代测序计算软件比具 有明显的优势,尤其是人类基因组的组装速度是同类软件的17-23倍,并首次在单个服务器 上实现了人类基因组组装工作。大幅降低了三代测序计算硬件平台要求,从而加速了三代测序的发展和应用。首次基于三代基因组数据系统提供小鼠等五个物种的 6mA甲基化图谱。(2)利用核糖体谱技术,系统解析非编码RNA的翻译潜能,首次阐明大量的 结合核糖体的非编码RNA具有翻译潜能以及生物学功能 ;系统分析777个公共核糖体谱数据,发表首个翻译组数据库;发表领域首篇核糖体谱分析工具综述。发表论文40余篇,影响因子>350分,引用约 1300次,现主持国家及省市级项目超过2000万元。

  研究经历

2013-至今,中山大 学,中山大学眼科中心,教授
2013年,入选“千人计划”青年项目全职回国
2012-2013,美国国家癌症研究院研究员(Investigator)
2010-2012,美国国家健康研究院正式职位科学家(Staff Scientist)
2007-2010,美国约翰霍普金斯大学博士后

  教育经历

2004-2007,新西兰林肯 大学计算系统生物学博士
2001-2003,新西兰林肯大学计算机一级荣誉学士
1993-1998,重庆医科大学临床医学专业本科

  科研成果

http://sysbio.gzzoc.com/publications.html

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Laboratory of Bioinformatics and Genomics, Sun Yat-sen University