Papers


Note: # equally contributed, * corresponding author


In submission

Yupeng Li#, Fan Wang#, Jiaqi Yang, Zirong Han, Linfeng Chen, Wenbing Jiang, Hao Zhou, Tong Li, Zehua Tang, Jianxiang Deng, Xin He, Gaofeng Cha, Jiekai Hu, Yong Hu, Linping Wu, Changyou Zhan, Caijun Sun, Yao He*, Zhi Xie*, Deep Generative Optimization of mRNA Codon Sequences for Enhanced Protein Production and Therapeutic Efficacy. In submission.
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Yuanyuan Yu#, Zhi Xie*, Spatial Transcriptomic Alignment, Integration, and de novo 3D Reconstruction by STAIR. In submission. https://doi.org/10.21203/rs.3.rs-3939678/v1.
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2024

Jingjing Zheng#, Tong Li#, Huijing Ye, Zehang Jiang, Wenbing Jiang, Huasheng Yang*, Zhikun Wu*, Zhi Xie*, Comprehensive identification of pathogenic variants in retinoblastoma by long- and short-read sequencing. Cancer Letters. 2024, August 28, Volume 598, 217121, DOI:https://doi.org/10.1016/j.canlet.2024.217121. (Q1, IF=9.1).
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Wenbing Jiang#, Dongchang Xiao#, Cheng Wu#, Jiaqi Yang, Xinghua Peng, Linfeng Chen, Jiamin Zhang, Gaofeng Zha, Wei Li, Rong Ju*, Mengqing Xiang*, Zhi Xie*, Circular RNA-Based Therapy Provides Sustained and Robust Neuroprotection for Retinal Ganglion Cell. Molecular Therapy-Nucleic Acids. 2024,June 17,DOI:https://doi.org/10.1016/j.omtn.2024.102258. (Q1, IF=8.8).
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Hao Zhou#, Wenhan Yang#, Limei Sun#, Li Huang, Songshan Li, Xiaoling Luo, Yili Jin, Wei Sun, Wenjia Yan, Jing Li, Xiaoyan Ding*, Yao He*, Zhi Xie*, RDLR: A Robust Deep Learning-Based Image Registration Method for Pediatric Retinal Images. Journal of Imaging Informatics in Medicine. 2024,1-15. (Q2, IF=4.4).
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Hao Zhou#, Yao He#, Xiaoxiao Cui*, Zhi Xie*, AGSAM: Agent-Guided Segment Anything Model for Automatic Segmentation in Few-Shot Scenarios. Bioengineering. 2024,11,447. (Q2, IF=3.8).
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Yuanyuan Yu, Yao He*, Zhi Xie*, Accurate Identification of Spatial Domain by Incorporating Global Spatial Proximity and Local Expression Proximity. Biomolecules. 2024,14,674. (Q1, IF=4.8).
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Ludong Yang#, Liang Yi#, Jiaqi Yang, Rui Zhang, Zhi Xie*, Hongwei Wang*, Temporal landscape and translational regulation of A-to-I RNA editing in mouse retina development. BMC Biology. 2024;22:106. (Q1, IF=4.4).
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Zhikun Wu#, Tong Li#, Zehang Jiang, Jingjing Zheng, Yizhou Gu, Yizhi Liu, Yun Liu, Zhi Xie*, Human pangenome analysis of sequences missing from the reference genome reveals their widespread evolutionary, phenotypic, and functional roles. Nucleic Acids Research. 2024;gkae086. (Q1, IF=14.9).
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Cheng Wu#, Tianxiang Tu#, Mingzhe Xie, Yiting Wang, Biao Yan, Yajun Gong, Jiayi Zhang, Xiaolai Zhou*, Zhi Xie*, Spatially resolved transcriptome of the aging mouse brain. Aging Cell. 2024;e14109. (Q1, IF=7.8).
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2023

Jianxia Li#, Cheng Wu#, Huabin Hu#, Ge Qin#, Xueqian Wu, Fan Bai, Jianwei Zhang, Yue Cai, Yan Huang, Chao Wang, Jiaqi Yang, Yizhao Luan, Zehang Jiang, Jiayu Ling, Zehua Wu, Yaoxu Chen, Zhi Xie, Yanhong Deng*, Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer. Cancer Cell. 2023;S1535-6108(23)00137-X.(Q1, IF=38.585).
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Yizhao Luan#, Zehua Tang#, Yao He, Zhi Xie*, Intra-Domain Residue Coevolution in Transcription Factors Contributes to DNA Binding Specificity. Microbiol Spectr. 2023;11(2):e0365122.(Q1, IF=9.043).
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Tong Li#, Yupeng Li#, Xiaoyi Zhu#, Yao He, Yanling Wu, Tianlei Ying*, Zhi Xie*, Artificial intelligence in cancer immunotherapy: Applications in neoantigen recognition, antibody design and immunotherapy response prediction. Semin Cancer Biol. 2023;91:50-69.(Q1, IF=17.012).
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Yuanyuan Chen#, Cheng Wu#, Shanzhen Peng, Dianlei Guo, Hong Ouyang, Yanhong Wei, Rong Ju*, Xiaoyan Ding*, Zhi Xie*, Chunqiao Liu*, Single-Cell Characterization of the Frizzled 5 (Fz5) Mutant Mouse and Human Persistent Fetal Vasculature (PFV). Invest Ophthalmol Vis Sci. 2023 Mar 1;64(3):8.(Q1, IF=4.299).
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Ying Yang#, Hongwei Wang#, Yuanliang Zhang, Lei Chen, Gennong Chen, Zhaoshi Bao, Yang Yang, Zhi Xie, Qian Zhao*, An Optimized Proteomics Approach Reveals Novel Alternative Proteins in Mouse Liver Development. Mol Cell Proteomics. 2023; 22(1): 100480.(Q1, IF=7.381).
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Xintong Zheng, Mingwei Wang, Shuting Liu, Haiqiao Chen, Yifei Li, Fa Yuan, Ludong Yang, Suo Qiu, Hongwei Wang, Zhi Xie, Mengqing Xiang* , A lncRNA-encoded mitochondrial micropeptide exacerbates microglia-mediated neuroinflammation in retinal ischemia/reperfusion injury. Cell Death Dis. 2023;14(2):126.(Q1, IF=8.5)
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2022

Zixuan Hu#, Jiaying Zhou#, Yupeng Li#, Yizhao Luan, Huan Li, Bo Jia, Zhi Xie*, Bin Cheng*, Tong Wu*, Peripheral immune signature resembles tumor microenvironment and predicts clinical outcomes in head and neck squamous cell carcinoma. Front Immunol. 2022;13:915207. (Q1, IF=8.787).
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Cheng Wu, Jiaqi Yang, Wei Xiao, Zehang Jiang, Shuxia Chen, Dianlei Guo, Ping Zhang, Chunqiao Liu, Huasheng Yang*, Zhi Xie*, Single-cell characterization of malignant phenotypes and microenvironment alteration in retinoblastoma. Cell Death and Disease, (2022) (Q1, IF=8.5).
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Yizhao Luan#, Nan Tang#, Jiaqi Yang#, Shuting Liu, Chichi Cheng, Yan Wang, Yanan Guo, Hongwei Wang, Mengqing Xiang, Rong Ju*, Zhi Xie* , Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells, Nucleic Acids Research, (2022) (Q1, IF=16.97).
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Breakthrough Article (Top 5% in NAR)
Faculty Opinions (Top 1% in Developmental Biology)





Mingzhe Xie#, Ludong Yang#, Gennong Chen#, Yan Wang, Zhi Xie*, Hongwei Wang* , RiboChat: a chat-style web interface for analysis and annotation of ribosome profiling data. Briefings in Bioinformatics, 2022 Mar 10;23(2):bbab559. (Q1, IF=11.62)
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2021

Zhikun Wu#, Zehang Jiang#, Tong Li#, Chuanbo Xie#, Liansheng Zhao#, Jiaqi Yang, Shuai Ouyang, Yizhi Liu, Tao Li*, Zhi Xie* , Structural variants in Chinese population and their impact on phenotypes, diseases and population adaptation. Nature Communications 12, 6501 (2021). https://doi.org/10.1038/s41467-021-26856-x (Q1, IF=14.91)
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Nicolas Dierckxsens#, Tong Li, Joris R. Vermeesch, Zhi Xie* , A benchmark of structural variation detection by long reads through a realistic simulated model. Genome Biol 22, 342 (2021). (Q1, IF=13.58)
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Kaining Chen#, Congying Chen#, Huihui Li, Jiaqi Yang, Mengqing Xiang, Hongwei Wang*, Zhi Xie* , Widespread translational control regulates retinal development in mouse, Nucleic Acids Research, 2021;, gkab749, https://doi.org/10.1093/nar/gkab749 (Q1, IF=16.97)
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Hongwei Wang#*, Yan Wang#, Jiaqi Yang#, Qian Zhao#, Nan Tang, Congying Chen, Huihui Li, Chichi Cheng, Mingzhe Xie, Yang Yang, Zhi Xie* , Tissue- and stage-specific landscape of the mouse translatome, Nucleic Acids Research, 2021 Jun 21;49(11):6165-6180. doi: 10.1093/nar/gkab482 (Q1, IF=16.97).
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Huihui Li#, Mingzhe Xie#, Yan Wang#, Ludong Yang, Zhi Xie*, Hongwei Wang* , riboCIRC: a comprehensive database of translatable circRNAs, Genome Biology, 2021 Mar 8;22(1):79. doi: 10.1186/s13059-021-02300-7. (Q1, IF=13.58).
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Lei Chen, Yuanliang Zhang, Ying Yang, Yang Yang, Huihui Li, Xuan Dong, Hongwei Wang, Zhi Xie, Qian Zhao* , An Integrated Approach for Discovering Noncanonical MHC-I Peptides Encoded by Small Open Reading Frames, Journal of the American Society for Mass Spectrometry, 2021 32 (9), 2346-2357. doi:10.1021/jasms.1c00076. (IF=3.10).
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2020

Guocai Yao, Wenliang Zhang, Minglei Yang, Huan Yang, Jianbo Wang, Haiyue Zhang, Lai Wei, Zhi Xie, Weizhong Li, MicroPhenoDB Associates Metagenomic Data with Pathogenic Microbes, Microbial Core Genes, and Human Disease Phenotypes, Genomics, Proteomics & Bioinformatics, 2020, November 12; https://doi.org/10.1016/j.gpb.2020.11.001 (IF=7.051).
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Yao He#, Hao Yuan#, Cheng Wu#, Zhi Xie*, DISC: a highly scalable and accurate inference of gene expression and structure for single-cell transcriptomes using semi-supervised deep learning, Genome Biology, 2020, July, 21(170) (Q1, IF=10.8).
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Surui Pei, Tao Liu, Xue Ren,Weizhong Li, Chongjian Chen*, Zhi Xie*, Benchmarking variant callers in next-generation and third-generation sequencing analysis, Briefings in Bioinformatics, 2020 July 23; https://doi.org/10.1093/bib/bbaa148 (Q1, IF=9.0).
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Xiaorong Lin, Xiaoxiao Dinglin, Siting Cao, Senyou Zheng, Cheng Wu, Wenying Chen, Qingjian Li, Qian Hu, Fang Zheng, Zhiyong Wu, De-Chen Lin, Yandan Yao, Xiaoding Xu, Zhi Xie, Qiang Liu, Herui Yao*, and Hai Hu*, Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade, Cell REPORTS, 2020 June 9;31(10):107753 (Q1, IF=8.1).
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2019

Hongwei Wang#*, Ludong Yang#, Yan Wang#, Leshi Chen#, Huihui Li, and Zhi Xie*, RPFdb v2.0: an updated database for genome-wide information of translated mRNA generated from ribosome profiling, Nucleic Acids Research, 2019 Jan 8;47(D1):D230-D234 (Q1, IF=11.5).
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Wenliang Zhang, Haiyue Zhang, Huan Yang, Miaoxin Li, Zhi Xie, Weizhong Li*, Computational resources associating diseases with genotypes, phenotypes and exposures, Briefings in Bioinformatics, 2019 Nov 27;20(6):2098-2115. doi: 10.1093/bib/bby071 (Q1, IF=9.0).
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2018

Qian Yu#, Bingying Lin#, Shangqian Xie, Song Gao, Wei Li, Yizhi Liu, Hongwei Wang, Danping Huang*, Zhi Xie*, A homozygous mutation p.Arg2167Trp in FREM2 causes isolated cryptophthalmos, Human Molecular Genetics, 2018, Jul 1;27(13):2357-2366 (Q1, IF=5.1).
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Jingxing Ou, John M. Ball#, Yizhao Luan#, Tantai Zhao#, Kiyoharu J. Miyagishima#, Yufeng Xu#, Huizhi Zhou, Jinguo Chen, Dana K. Merriman, Zhi Xie, Barbara S. Mallon, Wei Li*, iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications, Cell, 2018, May (Q1, IF=31.4).


Yongquan Lin#, Yan Wang#, Hui Li, Yuhang Chen, Wentao Qiao, Zhi Xie*, Juan Tan*, Zhilong Yang*, Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff, Protein & Cell, 2018, https://doi.org/10.1007/s13238-018-0535-6. (Q1, IF=10.2).

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Chensi Cao#, Feng Liu#, Hai Tan#, Deshou Song, Wenjie Shu, Weizhong Li, Yiming Zhou*, Xiaochen Bo*, Zhi Xie*, Deep Learning and its Applications in Biomedicine. Genomics, Proteomics & Bioinformatics, 2018, Volume 16, Issue 1, Pages 17-32 (Q1, IF=7.1).
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2017


Chuan-Le Xiao#*, Ying Chen#, Shang-qian Xie, Kai-Ning Chen, Yan Wang, Feng Luo*, and Zhi Xie*, MECAT: Fast mapping, error correction, and de novo assembly for single-molecule sequencing reads, Nature Methods, 2017, doi:10.1038/nmeth.4432. (Q1, IF=28.5).
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Zhiwen Jiang#, Jiaqi Yang#, Aimei Dai#, Yuming Wang, Wei Li, Zhi Xie*, Ribosome Profiling Reveals Translational Regulation of Mammalian Cells in Response to Hypoxic Stress, BMC Genomics, 2017 18:638, DOI 10.1186/s12864-017-3996-8 (Q2, IF=3.7).
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Hongwei Wang#*
, Yan Wang#, Zhi Xie*,Computational resources for ribosome profiling: from database to web server and software. Briefings in Bioinformatics, 2017, 1–12, doi: 10.1093/bib/bbx093. (Q1, IF=9.0).


Yizhao Luan,Jingxing Ou,Vincent P. Kunze,Fengyu Qiao,Yan Wang,Lai Wei,Wei Li,Zhi Xie*, Integrated transcriptomic and metabolomic analysis reveals adaptive changes of hibernating retinas. J Cell Physiol. 2017 May 25. doi: 10.1002/jcp.26030 (Q1, IF=5.5).
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Alice Cheng, Zhi Xie,Challenges in Orphan Drug Development and Regulatory Policy in China, Orphanet J Rare Dis. 2017 Jan 18;12(1):13. doi: 10.1186/s13023-017-0568-6. (Q1, IF=3.6).

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Xing F#, Luan Y#, Cai J, Wu S, Mai J, Gu J, Zhang H, Li K, Lin Y, Xiao X, Liang J, Li Y, Chen W, Tan Y, Sheng L, Lu B, Lu W, Gao M, Qiu P, Su X, Yin W, Hu J, Chen Z, Sai K, Wang J, Chen F, Chen Y, Zhu S, Liu D, Cheng S, Xie Z*, Zhu W*, Yan G*. The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes, Cell Rep. 2017 Jan 10;18(2):468-481. doi: 10.1016/j.celrep.2016.12.037 (Q1, IF=8.0).
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Wu FL, Liu Y, Jiang HW, Luan YZ, Zhang HN, ..., Xie Z, ..., Zhang XE, Tao SC., The Ser/Thr Protein Kinase Protein-Protein Interaction Map of M. tuberculosis, Mol Cell Proteomics. 2017, Aug;16(8): 1491-1506 (Q1, IF=5.2).
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Yang Z, Hou Y, Hao T, Rho HS, Wan J, Luan Y, Gao X, Yao J, Pan A, Xie Z, Qian J, Liao W, Zhu H, Zhou X*,A human proteome array approach to identifying key host proteins targeted by Toxoplasma kinase ROP18, Mol Cell Proteomics. 2017 Jan 13. doi: 10.1074/mcp.M116.063602 (Q1, IF=5.2).
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Hongwei Wang#*
, Yan Wang#, Shangqian Xie and Zhi Xie*, Global and cell-type specific properties of lincRNAs with ribosome occupancy,, Nucleic Acids Research, 2017 10.1093.gkw909 (Q1, IF=11.6).





2016

Aimei Dai#, Shuai Cao#, Pragyesh Dhungel#, Yizhao Luan, Yizhi Liu, Zhi Xie*, Zhilong Yang*, Ribosome Profiling Reveals Translational Upregulation of Cellular Oxidative Phosphorylation mRNAs During Vaccinia Virus-induced Host Shutoff, Journal of Virology, J Virol. 2016 Dec 21. pii: JVI.01858-16. doi: 10.1128/JVI.01858-16 (Q1, IF=4.4).
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Wenyan Hu#, Shengguo Li#, Ji Yeon Park, Sridhar Boppana, Ting Ni, Miaoxin Li, Jun Zhu, Bin Tian, Zhi Xie*, and Mengqing Xiang*, Dynamic landscape of alternative polyadenylation during retinal development, Cellular Molecular Life Science, Cell Mol Life Sci. 2016 Dec 18 (Q1, IF=6.7).
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Pohao Ye#, Yizhao Luan#, Chuanle Xiao#, Kaining Chen, Yizhi Liu, Zhi Xie*, MethSMRT: an integrative database for DNA N6-methyladenine and N4-methylcytosine generated by single-molecular real-time sequencing, Nucleic Acids Research,10.1093.gkw950 (Q1, IF=11.6).



Yingfei Wang*, Ran An, George K. Umanah, Hyejin Park, Kalyani Nambiar, Stephen M. Eacker, BongWoo Kim, Lei Bao, Maged M. Harraz, Calvin Chang, Rong Chen, Jennifer E. Wang, Tae-In Kam, Jun Seop Jeong, Zhi Xie, Stewart Neifert, Jiang Qian, Shaida A. Andrabi, Seth Blackshaw, Heng Zhu, Hongjun Song, Guo-li Ming, Valina L. Dawson*, Ted M. Dawson*, A Nuclease that Mediates Cell Death induced by DNA Damage and Poly(ADP-ribose) Polymerase-1, Science, Oct 7;354(6308) (Q1, IF=37.2).
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The MetaSUB International Consortium. The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report, Microbiome, 2016, 4:24 (Q1, IF=9.1).
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2015

Woodard C, Liao G, Goodwin CR, Hu J, Xie Z, Dos Reis TF, Newman R, RhoH, Qian J, Zhu H, Hayward SD. A Screen for Extracellular Signal-Regulated Kinase-Primed GlycogenSynthase Kinase 3 Substrates Identifies the p53 Inhibitor iASPP.J Virol. 2015 Sep;89(18):9232-41 (Q1, IF=4.6).
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Xie SQ #, Nie P #, Wang Y #, Wang H, Li H, Yang Z, Liu Y *, Ren J *, Xie Z *.RPFdb: a database for genome wide information of translated mRNA generated from ribosome profiling. Nucleic Acids Res. 2015 Oct 3 (Q1, IF=10.2).


Yang Z, Cao S, Martens CA, Porcella SF, Xie Z, Ma M, Shen B, Moss B.J Deciphering poxvirus gene expression by RNA sequencing and ribosome profiling.J Virol. 2015 Jul;89(13):6874-86 (Q1, IF=4.6).
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2014


Tsang, J.*, Schwartzberg, P.*, Kotliarov, Y.# , Biancotto, A. #, Xie, Z. #, Germain, R. #, Wang, E. #, Olnes, M. #, Narayanan, M., Golding, H., Moir, S., Dickler, H., Perl, S., Cheung, F., The Baylor HIPC Center, The CHI Consortium, Global analyses of human immune variation reveal baseline predictors of post-vaccination responses. Cell. 157,499-513,2014 (Q1, IF=32.2).



Lee, Y.-I., Giovinazzo, D., Kang, H.C., Lee, Y., Jeong, J.S., Doulias, P.-T., Xie, Z. , Hu, J., Ghasemi, M., Ischiropoulos, H., Qian, J., Zhu, H., Blackshaw, S., Dawson, VL., Dawson, TM. Protein microarray characterization of the S-nitrosoproteome. Mol. Cell. Proteomics 13, 63–72. 2014 (Q1, IF=5.9).
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Ito S, Bollard CM, Carlsten M, Melenhorst JJ, Biancotto A, Wang E, Chen J, Kotliarov Y, Cheung F, Xie, Z. , Marincola F, Tanimoto K, Battiwalla M, Olnes MJ, Perl S, Schum P, Hughes TE, Keyvanfar K, Hensel N, Muranski P, Young NS, Barrett AJ., Ultra-low Dose Interleukin-2 Promotes Immune-modulating Function of Regulatory T Cells and Natural Killer Cells in Healthy Volunteers. Mol Ther. 2014 Apr 1. doi: 10.1038/mt.2014.50 (Q1, IF=6.9).
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2013

Newman, R.H. #, Hu, J. #, Rho, H.-S. #, Xie, Z.#, Woodard, C., Neiswinger, J., Cooper, C., Shirley, M., Clark, H.M., Hu, S., Hwang, W., Jeong, JS., Wu, G., Lin, J., Gao, X., Ni, Q., Goel, R., Xia, S., Ji, H., Dalby, KN., Birnbaum, MJ., Cole, PA., Knapp, S., Ryazanov, AG., Zack, DJ., Blackshaw, S., Pawson, T., Gingras, AC., Desiderio, S., Pandey, A., Turk, BE., Zhang, J., Zhu, H., Qian, J. Construction of human activity-based phosphorylation networks. Mol. Syst. Biol. 9. 2013 (Q1, IF=10.6).


2012

Tarrant, M.K., Rho, H.-S., Xie, Z., Jiang, Y.L., Gross, C., Culhane, J.C., Yan, G., Qian, J., Ichikawa, Y., Matsuoka, T., Zachara, N., Etzkorn, FA., Hart, GW., Jeong, JS., Blackshaw, S., Zhu, H., Cole, PA. Regulation of CK2 by phosphorylation and O-GlcNA cylation revealed by semisynthesis. Nat. Chemical Biol. 8, 262–269. 2012 (Q1, IF=12.9).
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Shamay, M., Liu, J., Li, R., Liao, G., Shen, L., Greenway, M., Hu, S., Zhu, J., Xie, Z., Ambinder, R.F., Qian, J., Zhu, H., Hayward, SD. A protein array screen for Kaposi’s sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening. J. Virol. 86, 5179–5191. 2012 (Q1, IF=5.1).
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Before 2012

Xie, Z., Hu, S., Qian, J., Blackshaw, S., Zhu, H. *, Systematic characterization of protein-DNA interactions. Cell. Mol. Life Sci. 68, 1657–1668. 2011 (Q1, IF=6.6).
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Li, R., Zhu, J., Xie, Z.., Liao, G., Liu, J., Chen, M.-R., Hu, S., Woodard, C., Lin, J., Taverna, S.D., Desai, P., Ambinder, RF., Hayward, GS., Qian, J., Zhu, H., Hayward, SD. Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication. Cell Host Microbe 10, 390–400. 2011 (Q1, IF=13.5).



Hyland, E.M., Molina, H., Poorey, K., Jie, C., Xie, Z., Dai, J., Qian, J., Bekiranov, S., Auble, D.T., Pandey, A., Boeke, JD. An evolutionarily “young”lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae. Genes & Development. 25, 1306–1319. 2011 (Q1, IF=11.7).
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Hu, S., Xie, Z., Qian, J., Blackshaw, S., Zhu, H. *, Functional protein microarray technology. Wiley Interdiscip. Rev. Syst. Biol. Med. 3, 255–268. 2011 (IF=4.2).
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Hu, S., Xie, Z., Blackshaw, S., Qian, J., Zhu, H.*. Characterization of Protein–DNA Interactions Using Protein Microarrays. Cold Spring Harb. Protoc. 2011, pdb. prot5614. 2011a.
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Xie, Z., Hu, S., Blackshaw, S., Zhu, H., Qian, J.*, hPDI: a database of experimental human protein–DNA interactions. Bioinformatics 26, 287–289. 2010 (Q1, IF=4.9).
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Xie, Z.*, Kulasiri, D., Samarasinghe, S., Qian, J., An unbiased sensitivity analysis reveals important parameters controlling periodicity of circadian clock. Biotechnol. Bioeng. 105, 250–259. 2010 (Q1, IF=3.7).
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Cover image


Xie, Z. *, Kulasiri, D., On exploring effects of molecular noise in a simple viral infection model. Int. J. Biomath. 3, 1–19. 2010 (Q2, IF=1.7).
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Lin, J. #, Xie, Z.., Zhu, H., Qian, J. *, Understanding protein phosphorylation on a systems level. Briefings Funct. Genomics 9, 32–42. 2010 (Q1, IF=4.1).
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Tian, Y., Tan, A.-C., Sun, X., Olson, M.T., Xie, Z., Jinawath, N., Chan, D.W., Shih, I.-M., Zhang, Z., Zhang, H.*, Quantitative proteomic analysis of ovarian cancer cells identified mitochondrial proteins associated with paclitaxel resistance. PROTEOMICS–Clinical Appl. 3, 1288–1295. 2009 (Q2, IF=1.9).
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Hu, S.#, Xie, Z.#., Onishi, A., Yu, X., Jiang, L., Lin, J., Rho, H., Woodard, C., Blackshaw, S., * Qian, J. *, Zhu, H. * , Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling. Cell 139, 610–622. 2009 (Q1, IF=31.2).



Kulasiri, D.*, Nguyen, L.K., Samarasinghe, S., Xie, Z., A review of systems biology perspective on genetic regulatory networks with examples. Curr. Bioinforma. 3, 197–225. 2008 (Q2, IF=1.9).
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Kulasiri, D., Xie, Z. *, Modelling Circadian Rhythms in Drosophila and Investigation of VRI and PDP1 Feedback Loops Using a New Mathematical Model. Math. Model. Nat. Phenom. 3, 1–26. 2008 (Q2, IF=0.7).
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Xie, Z., Kulasiri, D., Samarasinghe, S. & Rajanayaka, C. (2007). The Estimation of Parameters for Stochastic Differential Equations Using Neural Networks. Inverse. Probl. Sci. Eng. 15(6), 629-641 (Q3, IF=1.3).
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Xie, Z., Kulasiri, D. *, Modelling of circadian rhythms in Drosophila incorporating the interlocked PER/TIM and VRI/PDP1 feedback loops. J. Theor. Biol. 245, 290–304. 2007 (Q1, IF=2.3).




Laboratory of Bioinformatics and Genomics, Sun Yat-sen University(粤ICP备11021180号)